CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.29 | PH-domain like |
|
2.30.29.30 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Domain Context
CATH Clusters
| Superfamily | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| Functional Family | Vav guanine nucleotide exchange factor 2 |
Enzyme Information
UniProtKB Entries (2)
| P27870 |
VAV_MOUSE
Mus musculus
Proto-oncogene vav
|
| P63000 |
RAC1_HUMAN
Homo sapiens
Ras-related C3 botulinum toxin substrate 1
|
PDB Structure
| PDB | 2VRW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crucial Structural Role for the Ph and C1 Domains of the Vav1 Exchange Factor.
Embo Rep.
|
