CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
Superfamily | P-loop containing nucleotide triphosphate hydrolases |
Functional Family | Deoxynucleoside kinase |
Enzyme Information
2.7.1.145 |
Deoxynucleoside kinase.
based on mapping to UniProt Q9XZT6
ATP + a 2'-deoxyribonucleoside = ADP + a 2'-deoxyribonucleoside 5'-phosphate.
-!- The enzyme from embryonic cells of the fruit fly Drosophila melanogaster differs from other 2'-deoxyribonucleoside kinases (EC 2.7.1.76 and EC 2.7.1.113) in its broad specificity for all four common 2'-deoxyribonucleosides.
|
UniProtKB Entries (1)
Q9XZT6 |
DNK_DROME
Drosophila melanogaster
Deoxynucleoside kinase
|
PDB Structure
PDB | 2VP6 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J.
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