CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Nicotinamide riboside kinase 1

Enzyme Information

2.7.1.173
Nicotinate riboside kinase.
based on mapping to UniProt Q9NWW6
ATP + beta-D-ribosylnicotinate = ADP + nicotinate beta-D-ribonucleotide.
-!- The enzyme from yeast and human also has the activity of EC 2.7.1.22. -!- Formerly EC 2.7.1.n4.
2.7.1.22
Ribosylnicotinamide kinase.
based on mapping to UniProt Q9NWW6
ATP + 1-(beta-D-ribofuranosyl)-nicotinamide = ADP + beta-nicotinamide D-ribonucleotide.

UniProtKB Entries (1)

Q9NWW6
NRK1_HUMAN
Homo sapiens
Nicotinamide riboside kinase 1

PDB Structure

PDB 2QL6
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human nicotinamide riboside kinase
Khan, J.A., Xiang, S., Tong, L.
Structure