CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.420 | Nucleotidyltransferase; domain 5 | |
3.30.420.10 | Ribonuclease H-like superfamily/Ribonuclease H |
Domain Context
CATH Clusters
Superfamily | Ribonuclease H-like superfamily/Ribonuclease H |
Functional Family | Ribonuclease H1 |
Enzyme Information
3.1.26.4 |
Ribonuclease H.
based on mapping to UniProt O60930
Endonucleolytic cleavage to 5'-phosphomonoester.
-!- Acts on RNA-DNA hybrids.
|
UniProtKB Entries (1)
O60930 |
RNH1_HUMAN
Homo sapiens
Ribonuclease H1
|
PDB Structure
PDB | 2QKK |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell
|