CATH Classification

Domain Context

CATH Clusters

Superfamily FAD/NAD(P)-binding domain
Functional Family p-hydroxybenzoate hydroxylase

Enzyme Information

1.14.13.2
4-hydroxybenzoate 3-monooxygenase.
based on mapping to UniProt P00438
4-hydroxybenzoate + NADPH + O(2) = protocatechuate + NADP(+) + H(2)O.
-!- Most enzymes from Pseudomonas are highly specific for NAD(P)H (cf. EC 1.14.13.33).

UniProtKB Entries (1)

P00438
PHHY_PSEFL
Pseudomonas fluorescens
P-hydroxybenzoate hydroxylase

PDB Structure

PDB 2PHH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The coenzyme analogue adenosine 5-diphosphoribose displaces FAD in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation.
van der Laan, J.M., Schreuder, H.A., Swarte, M.B., Wierenga, R.K., Kalk, K.H., Hol, W.G., Drenth, J.
Biochemistry