CATH Domain 2nmbA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	protein numb isoform X1

Enzyme Information

UniProtKB Entries (1)

NUMB_DROME

Drosophila melanogaster

Protein numb

PDB Structure

PDB	2NMB
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity. Li, S.C., Zwahlen, C., Vincent, S.J., McGlade, C.J., Kay, L.E., Pawson, T., Forman-Kay, J.D. Nat.Struct.Biol.