CATH Domain 2n7dA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.20	Ubiquitin-like (UB roll)
	3.10.20.90	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family	protein DDI1 homolog 2 isoform X1

Enzyme Information

3.4.23.-

Aspartic endopeptidases.

based on mapping to UniProt Q5TDH0

UniProtKB Entries (1)

DDI2_HUMAN

Homo sapiens

Protein DDI1 homolog 2

PDB Structure

PDB	2N7D
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog. Siva, M., Svoboda, M., Veverka, V., Trempe, J.F., Hofmann, K., Kozisek, M., Hexnerova, R., Sedlak, F., Belza, J., Brynda, J., Sacha, P., Hubalek, M., Starkova, J., Flaisigova, I., Konvalinka, J., Saskova, K.G. Sci Rep