CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.5 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | |
1.20.5.510 | Single helix bin |
Domain Context
CATH Clusters
Superfamily | Single helix bin |
Functional Family | Ephrin type-A receptor 2 |
Enzyme Information
2.7.10.1 |
Receptor protein-tyrosine kinase.
based on mapping to UniProt P29317
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.
|
UniProtKB Entries (1)
P29317 |
EPHA2_HUMAN
Homo sapiens
Ephrin type-A receptor 2
|
PDB Structure
PDB | 2K9Y |
External Links | |
Method | SOLUTION NMR |
Organism | |
Primary Citation |
Left-Handed Dimer of EphA2 Transmembrane Domain: Helix Packing Diversity among Receptor Tyrosine Kinases
Biophys.J.
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