CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | 3-hydroxyisobutyrate dehydrogenase |
Enzyme Information
| 1.1.1.31 |
3-hydroxyisobutyrate dehydrogenase.
based on mapping to UniProt P31937
3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH.
|
UniProtKB Entries (1)
| P31937 |
3HIDH_HUMAN
Homo sapiens
3-hydroxyisobutyrate dehydrogenase, mitochondrial
|
PDB Structure
| PDB | 2I9P |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of human hydroxyisobutyrate dehydrogenase complexed with NAD+
To be Published
|
