CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.30 | Roll | |
2.30.30 | SH3 type barrels. | |
2.30.30.230 | Fumarylacetoacetase, N-terminal domain |
Domain Context
CATH Clusters
Superfamily | Fumarylacetoacetase, N-terminal domain |
Functional Family | Fumarylacetoacetase |
Enzyme Information
3.7.1.2 |
Fumarylacetoacetase.
based on mapping to UniProt P35505
4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate.
-!- Also acts on other 3,5- and 2,4-dioxo acids.
|
UniProtKB Entries (1)
P35505 |
FAAA_MOUSE
Mus musculus
Fumarylacetoacetase
|
PDB Structure
PDB | 2HZY |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.
Biochem.J.
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