CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family | serine proteases 1/2 |
Enzyme Information
| 3.4.21.49 |
Hypodermin C.
based on mapping to UniProt P08897
Hydrolysis of proteins including native collagen at Xaa-|-Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment.
-!- Little action on small molecule substrates of trypsin, chymotrypsin, elastase or microbial collagenases. -!- Belongs to peptidase family S1.
|
UniProtKB Entries (1)
| P08897 |
COGS_HYPLI
Hypoderma lineatum
Collagenase
|
PDB Structure
| PDB | 2HLC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
1.8 A structure of Hypoderma lineatum collagenase: a member of the serine proteinase family.
Acta Crystallogr.,Sect.D
|
