CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Tryptophan--tRNA ligase

Enzyme Information

6.1.1.2
Tryptophan--tRNA ligase.
based on mapping to UniProt Q9WYW2
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

Q9WYW2
SYW_THEMA
Thermotoga maritima MSB8
Tryptophan--tRNA ligase

PDB Structure

PDB 2G36
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.
Han, G.W., Yang, X.L., McMullan, D., Chong, Y.E., Krishna, S.S., Rife, C.L., Weekes, D., Brittain, S.M., Abdubek, P., Ambing, E., Astakhova, T., Axelrod, H.L., Carlton, D., Caruthers, J., Chiu, H.J., Clayton, T., Duan, L., Feuerhelm, J., Grant, J.C., Grzechnik, S.K., Jaroszewski, L., Jin, K.K., Klock, H.E., Knuth, M.W., Kumar, A., Marciano, D., Miller, M.D., Morse, A.T., Nigoghossian, E., Okach, L., Paulsen, J., Reyes, R., van den Bedem, H., White, A., Wolf, G., Xu, Q., Hodgson, K.O., Wooley, J., Deacon, A.M., Godzik, A., Lesley, S.A., Elsliger, M.A., Schimmel, P., Wilson, I.A.
Acta Crystallogr.,Sect.F