CATH Domain 2c07A00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	3-oxoacyl-[acyl-carrier-protein] reductase FabG

Enzyme Information

UniProtKB Entries (1)

Q8I2S7_PLAF7

Plasmodium falciparum 3D7

3-oxoacyl-[acyl-carrier-protein] reductase

PDB Structure

PDB	2C07
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Kinetic, Inhibition and Structural Studies on 3-Oxoacyl-Acp Reductase from Plasmodium Falciparum, a Key Enzyme in Fatty Acid Biosynthesis. Wickramasinghe, S.R., Inglis, K.A., Urch, J.E., Muller, S., Van Aalten, D.M.F., Fairlamb, A.H. Biochem.J.