CATH Classification

Domain Context

CATH Clusters

Superfamily PUA domain
Functional Family tRNA pseudouridine synthase B

Enzyme Information

5.4.99.25
tRNA pseudouridine(55) synthase.
based on mapping to UniProt P60340
tRNA uridine(55) = tRNA pseudouridine(55).
-!- Pseudourine synthase TruB from Escherichia coli specifically modifies uridine(55) in tRNA molecules. -!- The bifunctional archaeal enzyme also catalyzes the pseudouridylation of uridine(54). -!- It is not known whether the enzyme from Escherichia coli can also act on position 54 in vitro, since this position is occupied in E.coli tRNAs by thymine.

UniProtKB Entries (1)

P60340
TRUB_ECOLI
Escherichia coli K-12
TRNA pseudouridine synthase B

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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