CATH Domain 1z45A01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	UDP-glucose 4-epimerase Gal10

Enzyme Information

5.1.3.2	UDP-glucose 4-epimerase. based on mapping to UniProt P04397 UDP-alpha-D-glucose = UDP-alpha-D-galactose. -!- Also acts on UDP-2-deoxyglucose.
5.1.3.3	Aldose 1-epimerase. based on mapping to UniProt P04397 Alpha-D-glucose = beta-D-glucose. -!- Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose. -!- This enzyme catalyzes the first step in galactose metabolism by converting beta-D-galactose into alpha-D-galactose, which is the substrate for EC 2.7.1.6.

UniProtKB Entries (1)

GAL10_YEAST

Saccharomyces cerevisiae S288C

Bifunctional protein GAL10

PDB Structure

PDB	1Z45
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The molecular architecture of galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae. Thoden, J.B., Holden, H.M. J.Biol.Chem.