CATH Domain 1t9wA05

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1640	Multidrug efflux transporter AcrB transmembrane fold
	1.20.1640.10	Multidrug efflux transporter AcrB transmembrane domain

Domain Context

CATH Clusters

Superfamily	Multidrug efflux transporter AcrB transmembrane domain
Functional Family	Efflux pump membrane transporter

Enzyme Information

UniProtKB Entries (1)

ACRB_ECOLI

Escherichia coli K-12

Multidrug efflux pump subunit AcrB

PDB Structure

PDB	1T9W
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	A Periplasmic Drug-Binding Site of the AcrB Multidrug Efflux Pump: a Crystallographic and Site-Directed Mutagenesis Study Yu, E.W., Aires, J.R., McDermott, G., Nikaido, H. J.Bacteriol.