CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Complement factor D

Enzyme Information

3.4.21.20
Cathepsin G.
based on mapping to UniProt P08311
Specificity similar to chymotrypsin C.
-!- From azurophil granules of polymorphonuclear leukocytes. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P08311
CATG_HUMAN
Homo sapiens
Cathepsin G

PDB Structure

PDB 1T32
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
de Garavilla, L., Greco, M.N., Sukumar, N., Chen, Z.W., Pineda, A.O., Mathews, F.S., Di Cera, E., Giardino, E.C., Wells, G.I., Haertlein, B.J., Kauffman, J.A., Corcoran, T.W., Derian, C.K., Eckardt, A.J., Damiano, B.P., Andrade-Gordon, P., Maryanoff, B.E.
J.Biol.Chem.