CATH Domain 1szuD02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.640	Aspartate Aminotransferase; domain 2
	3.40.640.10	Type I PLP-dependent aspartate aminotransferase-like (Major domain)

Domain Context

CATH Clusters

Superfamily	Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family	4-aminobutyrate aminotransferase

Enzyme Information

2.6.1.48	5-aminovalerate transaminase. based on mapping to UniProt P22256 5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate.
2.6.1.19	4-aminobutyrate--2-oxoglutarate transaminase. based on mapping to UniProt P22256 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate. -!- Some preparations also act on beta-alanine, 5-aminopentanoate and (R,S)-3-amino-2-methylpropanoate.

UniProtKB Entries (1)

GABT_ECOLI

Escherichia coli K-12

4-aminobutyrate aminotransferase GabT

PDB Structure

PDB	1SZU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Kinetic and Crystallographic Analysis of Active Site Mutants of Escherichia coligamma-Aminobutyrate Aminotransferase. Liu, W., Peterson, P.E., Langston, J.A., Jin, X., Zhou, X., Fisher, A.J., Toney, M.D. Biochemistry