CATH Domain 1sq5D00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Pantothenate kinase

Enzyme Information

2.7.1.33

Pantothenate kinase.

based on mapping to UniProt P0A6I3

ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.

UniProtKB Entries (1)

COAA_ECOLI

Escherichia coli K-12

Pantothenate kinase

PDB Structure

PDB	1SQ5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites. Ivey, R.A., Zhang, Y.-M., Virga, K.G., Hevener, K., Lee, R.E., Rock, C.O., Jackowski, S., Park, H.-W. J.Biol.Chem.