CATH Domain 1rlwA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.150	C2 domain

Domain Context

CATH Clusters

Superfamily	C2 domain
Functional Family	Phospholipase A2

Enzyme Information

3.1.1.4	Phospholipase A(2). based on mapping to UniProt P47712 Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate. -!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.
3.1.1.5	Lysophospholipase. based on mapping to UniProt P47712 2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate.

UniProtKB Entries (1)

PA24A_HUMAN

Homo sapiens

Cytosolic phospholipase A2

PDB Structure

PDB	1RLW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2. Perisic, O., Fong, S., Lynch, D.E., Bycroft, M., Williams, R.L. J.Biol.Chem.