CATH Domain 1pbwB00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.555	Phosphatidylinositol 3-kinase; Chain A
	1.10.555.10	Rho GTPase activation protein

Domain Context

CATH Clusters

Superfamily	Rho GTPase activation protein
Functional Family	Phosphatidylinositol 3-kinase regulatory subunit alpha

Enzyme Information

UniProtKB Entries (1)

P85A_HUMAN

Homo sapiens

Phosphatidylinositol 3-kinase regulatory subunit alpha

PDB Structure

PDB	1PBW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit. Musacchio, A., Cantley, L.C., Harrison, S.C. Proc.Natl.Acad.Sci.USA