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1 keywords

CATH Domain 1p49A01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.720 Alkaline Phosphatase, subunit A
Homologous Superfamily 3.40.720.10 Alkaline Phosphatase, subunit A

Domain Context

CATH Clusters

Superfamily Alkaline Phosphatase, subunit A
Functional Family Arylsulfatase E

Enzyme Information

3.1.6.2
Steryl-sulfatase.
based on mapping to UniProt P08842
3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H(2)O = 3-beta- hydroxyandrost-5-en-17-one + sulfate.
-!- Also acts on some related steryl sulfates.

UniProtKB Entries (1)

P08842
STS_HUMAN
Homo sapiens
Steryl-sulfatase

PDB Structure

PDB 1P49
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Human Estrone Sulfatase Suggests Functional Roles of Membrane Association
Hernandez-Guzman, F.G., Higashiyama, T., Pangborn, W., Osawa, Y., Ghosh, D.
J.Biol.Chem.
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