CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.40.1360
Functional Family Alpha-mannosidase

Enzyme Information

3.2.1.24
Alpha-mannosidase.
based on mapping to UniProt Q29451
Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D- mannosides.
-!- Also hydrolyzes alpha-D-lyxosides and heptopyranosides with the same configuration at C-2, C-3 and C-4 as mannose.

UniProtKB Entries (1)

Q29451
MA2B1_BOVIN
Bos taurus
Lysosomal alpha-mannosidase

PDB Structure

PDB 1O7D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Structure of Bovine Lysosomal Alpha-Mannosidase Suggests a Novel Mechanism for Low-Ph Activation
Heikinheimo, P., Helland, R., Leiros, H.S., Leiros, I., Karlsen, S., Evjen, G., Ravelli, R., Schoehn, G., Ruigrok, R., Tollersrud, O.-K., Mcsweeney, S., Hough, E.
J.Mol.Biol.