CATH Classification

Domain Context

CATH Clusters

Superfamily Cupredoxins - blue copper proteins
Functional Family

Enzyme Information
Nitrite reductase (NO-forming).
based on mapping to UniProt Q53239
Nitric oxide + H(2)O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H(+).
-!- The reaction is catalyzed by two types of enzymes, found in the perimplasm of denitrifying bacteria. -!- One type comprises proteins containing multiple copper centers, the other a heme protein, cytochrome cd1. -!- Acceptors include c-type cytochromes such as cytochrome c-550 or cytochrome c-551 from Paracoccus denitrificans or Pseudomonas aeruginosa, and small blue copper proteins such as azurin and pseudoazurin. -!- Cytochrome cd1 also has oxidase and hydroxylamine reductase activities. -!- May also catalyze the reaction of EC since this is a well- known activity of cytochrome cd1. -!- Formerly EC, EC and EC

UniProtKB Entries (1)

Rhodobacter sphaeroides ATCC 17025
Copper-containing nitrite reductase

PDB Structure

External Links
Organism Escherichia
Primary Citation
The High resolution Crystal Structures of Nitrite Reductase and its mutant Met182Thr from Rhodobacter Sphaeroides Reveal a Gating Mechanism for the Electron Transfer to the Type 1 Copper Center
Guo, H., Olesen, K., Xue, Y., Shapliegh, J., Sjolin, L.
To be Published