CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.620 | HUPs |
Domain Context
CATH Clusters
| Superfamily | HUPs |
| Functional Family | Isoleucine--tRNA ligase |
Enzyme Information
| 6.1.1.5 |
Isoleucine--tRNA ligase.
based on mapping to UniProt P56690
ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile).
|
UniProtKB Entries (1)
| P56690 |
SYI_THET8
Thermus thermophilus HB8
Isoleucine--tRNA ligase
|
PDB Structure
| PDB | 1JZS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase.
J.Biol.Chem.
|
