CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphoenolpyruvate-binding domains
Functional Family Isocitrate lyase

Enzyme Information

4.1.3.1
Isocitrate lyase.
based on mapping to UniProt P0A9G6
Isocitrate = succinate + glyoxylate.
-!- The isomer of isocitrate involved is (1R,2S)-1-hydroxypropane-1,2,3- tricarboxylate.

UniProtKB Entries (1)

P0A9G6
ACEA_ECOLI
Escherichia coli K-12
Isocitrate lyase

PDB Structure

PDB 1IGW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure and domain organization of Escherichia coli isocitrate lyase.
Britton, K.L., Abeysinghe, I.S., Baker, P.J., Barynin, V., Diehl, P., Langridge, S.J., McFadden, B.A., Sedelnikova, S.E., Stillman, T.J., Weeradechapon, K., Rice, D.W.
Acta Crystallogr.,Sect.D