CATH Domain 1i7dA02
|1.10.460||Topoisomerase I; domain 2|
|1.10.460.10||Topoisomerase I, domain 2|
|Superfamily||Topoisomerase I, domain 2|
|Functional Family||DNA topoisomerase 3|
based on mapping to UniProt P14294
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.
-!- These enzymes bring about the conversion of one topological isomer of DNA into another, e.g., the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of complementary sequences, cf. EC 22.214.171.124. -!- Formerly EC 126.96.36.199.
UniProtKB Entries (1)
Escherichia coli K-12
DNA topoisomerase 3
Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule.