CATH Domain 1fb8A00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

Enzyme Information

UniProtKB Entries (1)

DAPP1_HUMAN

Homo sapiens

Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

PDB Structure

PDB	1FB8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains. Ferguson, K.M., Kavran, J.M., Sankaran, V.G., Fournier, E., Isakoff, S.J., Skolnik, E.Y., Lemmon, M.A. Mol.Cell