CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.70 | Cathepsin B; Chain A |
|
3.90.70.10 | Cysteine proteinases |
Domain Context
CATH Clusters
| Superfamily | Cysteine proteinases |
| Functional Family | Cathepsin Z |
Enzyme Information
| 3.4.18.1 |
Cathepsin X.
based on mapping to UniProt Q9UBR2
Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.
-!- Deamidates Z-Arg-NH(2), but shows no action on the arylamide derivatives. -!- Inhibited by thiol-blocking reagents. -!- Belongs to peptidase family C1.
|
UniProtKB Entries (1)
| Q9UBR2 |
CATZ_HUMAN
Homo sapiens
Cathepsin Z
|
PDB Structure
| PDB | 1EF7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of cathepsin X: a flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease.
Structure Fold.Des.
|
