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CATH Superfamily 3.40.50.2300

Response regulator

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 151899: PTS system mannitol-specific EIICBA component

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.195, 2.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.201, 2.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 and 2.7.1.208. [EC: 2.7.1.69]
    		1886 A0A011Q8B7 A0A011Q8B7 A0A017I918 A0A017I918 A0A023Z2E7 A0A023Z2E7 A0A023Z4P1 A0A023Z4P1 A0A024KR32 A0A024KR32
    (1876 more...)
    Protein-N(pi)-phosphohistidine--D-mannose phosphotransferase. [EC: 2.7.1.191]
    [Protein]-N(pi)-phospho-L-histidine + D-mannose(Side 1) = [protein]-L- histidine + D-mannose 6-phosphate(Side 2).
    • This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).
    • The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.
    • The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.
    • Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.
    • The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
    • Formerly EC 2.7.1.69.
    		 820 A0A023Z2E7 A0A023Z2E7 A0A023Z4P1 A0A023Z4P1 A0A025CIN4 A0A025CIN4 A0A025CRP3 A0A025CRP3 A0A026S185 A0A026S185
    (810 more...)
    Protein-N(pi)-phosphohistidine--D-mannitol phosphotransferase. [EC: 2.7.1.197]
    [Protein]-N(pi)-phospho-L-histidine + D-mannitol(Side 1) = [protein]-L- histidine + D-mannitol 1-phosphate(Side 2).
    • This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).
    • The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.
    • The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate--protein phosphotransferase).
    • Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.
    • The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
    • Formerly EC 2.7.1.69.
    		 424 A0A025CRP3 A0A025CRP3 A0A026UTL5 A0A026UTL5 A0A026UXH9 A0A026UXH9 A0A027U892 A0A027U892 A0A028AEP9 A0A028AEP9
    (414 more...)
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