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CATH Superfamily 3.30.160.60

Classic Zinc Finger

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Classic Zinc Finger
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
23451
Zinc finger protein 3
86067
EC
3D
 1x6eA01 - 85.4
23446
Early growth response 1
76903
EC
3D
 2jp9A02 - 94.1
431
Site-specific recombinase, phage integrase family
16462
3D
 1b69A00 - 15.6
11224
Putative thymidylate kinase
16169
EC
3D
 2r1fA03 - 52.4
9930
Putative thymidylate kinase
15522
EC
 - - 19.2
23684
C2H2 zinc finger protein
4641 - - 96.8
23366
Kruppel-like factor 1
Erythroid
3938
3D
 1llmC01 - 84.1
9152
Sp1 transcription factor variant
3759
EC
 - - 82.7
23400
Kruppel-like factor 1
Erythroid
2287
3D
 2epaA02 - 81.1
23769
Myeloid zinc finger 1
1296 - - 84.9
23167
Kruppel-like factor 2
Lung
1290
3D
 2wbsA00 - 69.0
23781
Zic family member 1
1258 - - 93.0
23352
Kruppel-like transcription factor 4a
1154
3D
 2wbuA01 - 90.8
23361
Kruppel-like factor 3
Basic
1141 - - 84.3
15082
Oncorhynchus mykiss genomic scaffold, scaffold_1210
1015
EC
 - - 68.3
23567
Sp3 transcription factor variant
1002
EC
 - - 87.9
23237
Zinc finger protein Helios
954
EC
 - - 84.2
23770
Zinc finger transcription factor Gli3
943
3D
 2gliA01 - 81.5
23404
Probable DNA-binding protein creA
927 - - 88.0
23416
Escargot/snail protein homolog
912 - - 61.8
23428
Paternally-expressed gene 3 protein
881
3D
 2em6A01 - 60.7
1476
Predicted integrase
816
3D
 1kjkA00 - 29.8
23355
Zinc finger protein GIS
792 - - 87.3
23753
Zinc finger protein 41
761 - - 77.6
23395
Zic family member 1
739
3D
 2ej4A01 - 94.0
23756
Zinc finger protein SNAI1
686 - - 94.2
17893
Zinc finger protein AEBP2
667 - - 84.3
8383
Protein snail homolog Sna
657 - - 57.6
23369
Zinc finger family protein
655 - - 85.9
23318
Zinc finger protein GLI3
562 - - 72.6
23396
Oncorhynchus mykiss genomic scaffold, scaffold_2685
502 - - 91.5
23367
Zinc finger protein SNAI2
479 - - 78.2
11640
Krueppel-like factor 6 isoform A
457 - - 73.9
23192
Zinc finger protein 704
431 - - 66.0
23344
Zinc finger protein 148
388 - - 84.6
23115
C2H2-type zinc finger protein
358 - - 92.0
875
Truncated integrase
341 - - 16.2
1275
Zinc finger homeobox protein 4
325 - - 53.0
23561
Zinc finger protein 532
293 - - 88.0
23080
Teashirt zinc finger homeobox 3
290 - - 82.7
23243
Zinc finger and BTB domain-containing protein 7A
275 - - 84.2
23315
Zinc finger protein 503
272 - - 46.0
23337
Recombination activating gene 1
270
EC
3D
 1rmdA02 - 98.6
23340
Zinc finger protein 740
268 - - 80.5
19875
Zinc finger protein Pegasus
234 - - 42.5
23376
Zinc finger transcription factor
221 - - 89.7
19074
Zinc finger protein 536
216 - - 0.0
23083
Zinc finger protein 423
215 - - 57.5
23814
RE1-silencing transcription factor variant E1a/E2/E3/E5
201 - - 90.4
23075
Zinc finger protein ZFPM1
184 - - 49.2
14108
Kruppel-like factor 1
Erythroid
159 - - 82.4
23194
Transcription factor Ovo-like 2
158 - - 80.2
5877
Krueppel-like factor 5
157 - - 78.5
23316
Zinc finger protein GLI3
154 - - 34.3
14260
Kruppel-like factor 11
150 - - 54.7
2151
Zinc finger E-box-binding homeobox 1
149 - - 69.7
8171
Zinc finger protein 367
148 - - 67.1
13975
Cyclic AMP-dependent transcription factor ATF-7
137 - - 22.7
23138
Uncharacterized protein
129 - - 31.7
1523
Zinc finger protein 532
128 - - 56.3
23530
Bozf1-prov protein
122 - - 44.5
16613
Zinc finger protein 688
121 - - 49.1
23468
Zinc finger protein MSN2/4
120 - - 55.3
10465
GC Binding Protein - 23b
119
3D
 2epaA01 - 49.1
23137
Zinc finger protein 423
113
3D
 2mdgA00 - 28.4
6084
Zinc finger and BTB domain-containing protein 5
111 - - 33.2
16355
Early growth response protein 4
108 - - 46.8
2061
Zinc finger family protein
101 - - 15.5
6075
Charlatan, isoform I
99 - - 88.0
13545
Oncorhynchus mykiss genomic scaffold, scaffold_129
97 - - 38.6
6267
Transcriptional repressor protein YY1
93 - - 65.0
5369
Nrg1p
91 - - 12.8
9925
Oncorhynchus mykiss genomic scaffold, scaffold_11966
88 - - 58.4
2247
Zinc finger protein 639
87 - - 47.6
23733
Zinc finger and BTB domain-containing protein 9
79 - - 49.1
23580
Zinc finger protein 438
77 - - 62.7
7923
Putative transcription factor sp8,sp9
72 - - 47.4
5296
Pleiomorphic adenoma protein-like 2
70 - - 34.4
23818
Pleiomorphic adenoma protein-like 2
69 - - 75.0
13786
Recombination activating protein 1
65
EC
 - - 77.4
19822
Zinc finger protein ZFAT
63
3D
 2rsiA01 - 24.7
3635
Zinc finger and BTB domain-containing protein 6
61 - - 56.0
1561
PR domain zinc finger protein 14
61 - - 38.6
19906
Krueppel-like factor 13
60 - - 36.5
8613
Uncharacterized protein
59 - - 20.5
23151
Zinc finger protein GLIS2
57 - - 31.0
3899
Zinc finger protein 512
53 - - 11.3
3282
Zinc finger protein 592
48 - - 32.5
2867
Zinc finger protein ZFAT
46 - - 22.3
1036
Broad-complex isoform Z1
42 - - 60.5
7678
Zinc finger protein WIP5
42 - - 15.5
8283
Krueppel-like factor 11
40 - - 55.7
22310
Zinc finger protein hangover
40 - - 61.4
3902
Zinc-responsive transcriptional regulator ZAP1
39 - - 27.9
2631
Zinc finger protein 644
39 - - 39.5
624
Zinc finger protein ZFPM2
38 - - 16.3
23199
Zinc finger protein 423
37 - - 12.1
23341
26S proteasome regulatory subunit RPN4
32 - - 42.3
4294
Zinc finger, C2H2-like containing protein
30 - - 51.9
1086
26S proteasome regulatory subunit RPN4
30 - - 1.8
23771
Zinc finger protein Elbow
28 - - 8.3
6892
Transcriptional regulator, putative
26 - - 63.1
127
RE1-silencing transcription factor variant E1a/E2/E3/N3c/E4
24 - - 28.9
23963
Zinc finger protein 423
21 - - 39.9
23182
Zinc finger protein 521
20 - - 19.0
6079
Zinc finger protein 462
20 - - 37.2
23339
Calcineurin transcriptional regulator CRZ1
20 - - 47.5
5375
Zinc finger protein 653
19 - - 19.5
23089
Zinc finger protein
18 - - 60.6
23331
Krueppel-like factor 11
17 - - 57.0
3429
Zinc finger protein, Y-linked
16 - - 8.2
6579
Zinc finger protein 447, isoform CRA_a
15 - - 19.8
2144
Zinc finger protein 592
14 - - 21.6
7651
Zinc finger protein 846
14 - - 26.6
877
E14 prophage predicted integrase
14 - - 9.0
4299
Chromosome alignment-maintaining phosphoprotein 1
14 - - 25.3
23286
Zinc finger and BTB domain-containing protein 7A
13 - - 34.2
6747
Zinc finger protein 512
10 - - 28.0
23875
Chorion transcription factor Cf2
10 - - 54.2
23708
GG22698
10 - - 2.1
23924
Molting defective, isoform A
8 - - 17.0
23184
PR domain zinc finger protein 16
8 - - 0.0
5390
Molting defective, isoform F
6 - - 8.3
23575
Zinc finger protein SNAI1
6 - - 31.8
19050
Uncharacterized protein
6 - - 7.0
8314
Zinc finger protein 571
6 - - 4.2
23183
Zinc finger protein 536
5 - - 0.0
23420
Uncharacterized zinc finger protein At4g06634
5 - - 0.0
4014
Early hematopoietic zinc finger
4 - - 40.5
23704
Transcription factor IIIA
4 - - 10.4
23656
Zinc finger transcription factor Trps1
4 - - 6.1
19635
Zinc finger protein 770
4 - - 0.0
1960
Zinc finger protein 592
4 - - 24.9
8534
Vielfaltig, isoform D
4 - - 25.7
6752
Zinc finger and BTB domain-containing protein 8A
3 - - 11.9
23353
RE1-silencing transcription factor A
3 - - 0.0
6210
EGL-43, isoform b
3 - - 15.2
23703
Zinc finger protein 775
3 - - 0.0
4716
RE1-silencing transcription factor variant E1a/E2a/E2k
3 - - 2.1
10567
Zinc finger protein 692
3 - - 37.1
4359
Transcription factor grauzone
2 - - 0.0
21580
Putative zinc finger protein 818
2 - - 15.5
3565
Transcriptional regulating factor 1
2 - - 6.7
4817
Uncharacterized protein
2 - - 0.0
9527
Predicted protein
2 - - 13.7
23450
Zinc finger protein ZIC 5
2 - - 1.2
16612
GE13591
2 - -
12691
Uncharacterized protein
2 - - 0.0
2850
Zinc finger protein 653
2 - - 0.0
23552
Zinc finger protein STP4
2 - - 4.6
19079
Zinc finger protein 217
2 - - 3.6
18045
C2H2 zinc-finger protein
2 - - 19.5
20887
Uncharacterized protein
2 - - 0.0
17991
Zinc finger protein AEBP2
1 - -
23618
Putative uncharacterized protein
1 - - 0.0
23226
Zinc finger protein ZAT1
1 - - 0.0
23860
BCR1
1 - - 0.0
23085
Uncharacterised protein
1 - -
9238
Snail protein
1 - - 0.0
2389
CG11247, isoform D
1 - - 0.0
7515
Replication initiator 1
1 - - 0.0
21582
Putative zinc finger protein 826
1 - - 0.0
5371
Zinc finger and BTB domain-containing protein 44
1 - - 0.0
1320
CG43347, isoform D
1 - -
11453
GG14748
1 - - 0.0
15655
Uncharacterized protein
1 - - 0.0
23172
Early growth response protein 1-B
1 - - 0.0
14618
Putative uncharacterized protein
1 - - 0.0
13610
Zinc finger and BTB domain-containing protein 1
1 - -
7613
Zinc finger protein 227
1 - - 0.0
23342
Sal-like protein 3
1 - - 0.0
11216
Putative transcription factor Ovo-like 1
1 - - 0.0
23689
Protein BM-ZAG-1, isoform b
1 - - 0.0
23682
Uncharacterized protein
1 - - 0.0
23147
Uncharacterized protein
1 - - 0.0
23073
Protein teflon
1 - - 0.0
10400
Putative zinc finger protein
1 - - 0.0
23244
PR domain zinc finger protein 14
1 - - 0.0
12664
Zinc finger protein 639
1 - - 0.0
2741
Zinc finger protein 576
1 - -
23118
Zinc finger E-box-binding homeobox 1
1 - - 0.0
3159
GJ19353
1 - - 0.0
6076
Sal-like protein 3
1 - -
17177
CG10431, isoform A
1 - - 0.0
6941
PR domain zinc finger protein 15
1 - -
5319
Zinc finger and BTB domain-containing protein 44
1 - -
2024
Pogo transposable element with ZNF domain
1 - -
16207
Uncharacterized protein
1 - - 0.0
23713
Pleiomorphic adenoma gene-like 1
1 - - 0.0
10020
Uncharacterized protein
1 - - 0.0
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