×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family ATP-dependent DNA helicase RuvB

Enzyme Information

3.6.4.12
DNA helicase.
based on mapping to UniProt Q9PMT7
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).

UniProtKB Entries (1)

Q9PMT7
RUVB_CAMJE
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Holliday junction ATP-dependent DNA helicase RuvB

PDB Structure

PDB 3PFI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
2.7 Angstrom resolution crystal structure of a probable holliday junction DNA helicase (ruvB) from Campylobacter jejuni subsp. jejuni NCTC 11168 in complex with adenosine-5'-diphosphate
Halavaty, A.S., Wawrzak, Z., Skarina, T., Onopriyenko, O., Edwards, A., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
To be Published
CATH-Gene3D is a Global Biodata Core Resource Learn more...