CATH Domain 3c3wA02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	Two-component transcriptional regulatory protein DevR

Enzyme Information

UniProtKB Entries (1)

DEVR_MYCTU

Mycobacterium tuberculosis H37Rv

Transcriptional regulatory protein DevR (DosR)

PDB Structure

PDB	3C3W
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation Wisedchaisri, G., Wu, M., Sherman, D.R., Hol, W.G. J.Mol.Biol.