CATH Domain 1g3uA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	dTMP kinase

Enzyme Information

2.7.4.9

dTMP kinase.

based on mapping to UniProt P9WKE1

ATP + dTMP = ADP + dTDP.

UniProtKB Entries (1)

KTHY_MYCTU

Mycobacterium tuberculosis H37Rv

Thymidylate kinase

PDB Structure

PDB	1G3U
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 A resolution. Li de la Sierra, I., Munier-Lehmann, H., Gilles, A.M., Barzu, O., Delarue, M. J.Mol.Biol.