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CATH Classification

Domain Context

CATH Clusters

Superfamily Putative phosphatase; domain 2
Functional Family Haloacid dehalogenase, type II

Enzyme Information

3.8.1.2
(S)-2-haloacid dehalogenase.
based on mapping to UniProt Q60099
(S)-2-haloacid + H(2)O = (R)-2-hydroxyacid + halide.
-!- Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 (see also EC 3.8.1.9, EC 3.8.1.10 and EC 3.8.1.11).

UniProtKB Entries (1)

Q60099
HAD_XANAU
Xanthobacter autotrophicus
(S)-2-haloacid dehalogenase

PDB Structure

PDB 1AQ6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Three-dimensional structure of L-2-haloacid dehalogenase from Xanthobacter autotrophicus GJ10 complexed with the substrate-analogue formate.
Ridder, I.S., Rozeboom, H.J., Kalk, K.H., Janssen, D.B., Dijkstra, B.W.
J.Biol.Chem.
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