The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rho GTPase activation protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
832 - - 93.5
2
674
3D
3iugB00 - 83.4
3
617
3D
3byiD00 - 86.8
4
484 - - 81.3
5
469
3D
3cxlA03 - 87.1
6
435
3D
1f7cA00 - 90.1
7
415
3D
3kuqA00 - 71.3
8
370 - - 81.1
9
348
3D
5hpyD00 - 68.3
10
323 - - 82.8
11
305 - - 81.2
12
281
3D
3qisA02 - 94.2
13
278 - - 68.4
14
256 - - 85.0
15
255 - - 81.4
16
234 - - 74.1
17
230 - - 79.6
18
218 - - 92.1
19
214
3D
5jcpB01 - 77.0
20
204 - - 33.2
21
204
3D
3fk2D00 - 70.6
22
172 - - 70.4
24
163
3D
6r3vA00 - 80.2
23
159 - - 48.5
25
150
3D
3msxB00 - 89.7
26
141 - - 89.8
27
137
3D
2mbgA01 - 91.0
29
131 - - 77.0
28
131 - - 70.9
30
97 - - 77.7
31
96 - - 81.6
34
93
3D
5c2jA00 - 85.2
32
91 - - 76.3
33
Lrg11
88 - - 73.5
35
88
3D
1pbwB00 - 85.1
36
70 - - 80.6
37
70
3D
2xs6A00 - 81.8
38
64 - - 62.6
39
60 - - 89.6
40
55 - - 26.2
41
Rgd1
54 - - 53.0
42
54
3D
3eapD00 - 43.5
43
46 - - 87.1
44
41 - - 80.0
45
35 - - 98.1
46
30 - - 63.2
47
30 - - 8.0
48
26 - - 10.1
49
26 - - 71.2
50
25 - - 78.8
51
25 - - 53.0
52
25 - - 47.8
53
24 - - 81.0
55
21 - - 87.6
54
21 - - 18.6
56
20 - - 79.0
57
20 - - 80.0
58
19 - - 84.9
61
17 - - 5.2
60
17 - - 71.1
59
17 - - 40.8
63
16 - - 71.8
62
16 - - 17.0
64
16 - - 13.0
65
15 - - 15.8
66
Bem3
15 - - 53.3
72
14
3D
5my3A00 - 29.0
67
14 - - 79.4
68
13 - - 86.1
69
13 - - 92.1
70
13 - - 74.3
71
13 - - 80.7
74
12 - - 11.6
75
12 - - 30.8
73
12 - - 51.5
76
11 - - 29.4
77
10 - - 84.9
78
9 - - 29.9
80
9 - - 73.3
81
9 - - 23.5
79
9 - - 0.0
82
8 - - 4.6
84
8 - - 24.0
83
8 - - 15.6
85
8 - - 48.6
86
8 - - 13.7
87
8 - - 44.1
89
7 - - 3.2
91
7 - - 4.7
92
7 - - 5.4
99
7 - - 8.3
90
7 - - 5.3
100
7 - - 4.5
93
7 - - 9.6
101
7 - - 58.3
96
7 - - 9.9
94
7 - - 10.7
95
7 - - 5.1
98
7 - - 17.2
97
7 - - 12.9
88
7 - - 3.0
105
6 - - 80.4
102
6 - - 2.6
103
6 - - 3.6
108
6 - - 60.9
106
6 - - 1.3
107
6 - - 0.0
104
6 - - 0.0
112
5 - - 79.1
111
5 - - 8.7
113
5 - - 5.4
110
5 - - 2.5
118
5 - - 55.0
116
5 - - 11.6
117
5 - - 1.5
109
5 - - 82.0
115
Rac-GTPase-activating protein
5 - - 13.2
114
5 - - 0.6
128
4 - - 69.2
132
4 - - 69.1
129
4 - - 75.4
124
beta
4 - - 30.4
131
4 - - 81.0
119
4 - - 60.2
125
4 - - 10.6
126
4 - - 2.2
133
4 - - 77.3
134
4 - - 22.5
127
4 - - 14.2
120
4 - - 63.9
121
4 - - 67.4
130
4 - - 74.5
122
4 - - 27.8
123
4 - - 0.0
142
3 - - 0.0
139
3 - - 50.3
141
RhoGAP
3 - - 5.7
144
3 - - 0.7
143
3 - - 9.3
136
3 - - 0.0
137
3 - - 0.4
147
3 - - 4.9
135
3 - - 6.7
145
3 - - 16.6
146
3 - - 14.5
138
3 - - 0.0
140
3 - - 17.5
170
2 - - 0.0
184
2 - - 41.6
181
2 - - 0.4
158
2 - - 0.0
165
2 - - 0.0
149
2 - - 19.8
168
2 - - 39.9
178
2 - - 0.0
183
2 - - 31.4
148
2 - - 40.1
157
2 - - 0.0
179
2 - - 2.9
177
2 - - 0.0
163
2 - - 0.0
186
2 - - 39.7
156
2 - - 7.4
171
2 - - 0.6
176
2 - - 0.5
166
2 - - 8.2
185
2 - - 38.5
153
2 - - 1.4
180
2 - - 0.0
187
2 - - 22.4
155
2 - - 0.0
175
2 - - 0.0
154
2 - - 1.8
152
2 - - 8.9
161
2 - - 18.9
174
2 - - 0.0
164
2 - - 1.5
160
2 - - 11.9
151
2 - - 25.3
182
2 - - 0.0
167
2 - - 2.9
173
2 - - 8.4
150
2 - - 18.7
159
2 - - 0.0
162
2 - - 27.0
169
2 - - 19.0
172
2 - - 0.0
191
1 - - 0.0
262
1 - - 0.0
232
1 - - 0.0
225
1 - - 0.0
207
1 - - 0.0
222
1 - - 0.0
217
1 - - 0.0
209
1 - - 0.0
252
1 - - 0.0
224
1 - - 0.0
263
1 - - 0.0
192
1 - - 0.0
267
1 - - 0.0
233
1 - - 0.0
199
1 - - 0.0
204
1 - - 0.0
253
1 - - 0.0
258
1 - - 0.0
248
1 - - 0.0
236
1 - - 0.0
234
1 - - 0.0
193
1 - - 0.0
260
1 - - 0.0
205
1 - - 0.0
227
1 - - 0.0
264
1 - - 0.0
259
1 - - 0.0
249
1 - - 0.0
214
1 - - 0.0
196
1 - - 0.0
194
1 - - 0.0
226
1 - - 0.0
244
1 - - 0.0
237
1 - - 0.0
235
1 - - 0.0
265
1 - - 0.0
256
1 - - 0.0
215
1 - - 0.0
270
1 - - 0.0
261
1 - - 0.0
246
1 - - 0.0
212
1 - - 0.0
257
1 - - 0.0
198
1 - - 0.0
202
1 - - 0.0
229
1 - - 0.0
247
1 - - 0.0
210
1 - - 0.0
271
1 - - 0.0
242
1 - - 0.0
254
1 - - 0.0
213
1 - - 0.0
200
1 - - 0.0
195
1 - - 0.0
188
1 - - 0.0
243
1 - - 0.0
203
1 - - 0.0
228
1 - - 0.0
268
1 - - 0.0
238
1 - - 0.0
211
1 - - 0.0
218
1 - - 0.0
189
1 - - 0.0
221
1 - - 0.0
255
1 - - 0.0
250
1 - - 0.0
240
1 - - 0.0
230
1 - - 0.0
239
1 - - 0.0
269
1 - - 0.0
219
1 - - 0.0
206
1 - - 0.0
220
1 - - 0.0
197
1 - - 0.0
251
1 - - 0.0
245
1 - - 0.0
208
1 - - 0.0
241
1 - - 0.0
201
1 - - 0.0
266
1 - - 0.0
190
1 - - 0.0
231
1 - - 0.0
223
1 - - 0.0
216
1 - - 0.0