The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cyclin-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
2505 - - 97.7
4
494
3D
2pk2D02 - 93.6
2
478 - - 91.9
3
466 - - 97.3
5
433 - - 96.6
6
423 - - 99.5
8
414
3D
5iydM02 - 98.5
9
412
3D
6cytB01 - 81.3
7
411 - - 93.9
10
396 - - 97.4
11
393 - - 77.7
12
373 - - 90.8
13
362 - - 97.2
37
354
3D
4ii5D01 - 92.2
15
352
3D
5xs2B02 - 82.1
14
329 - - 81.8
17
308
3D
5xs2B01 - 82.3
16
290 - - 72.0
18
Predicted
288
3D
6ckxD02 - 82.2
19
276
3D
5iydM01 - 88.4
20
263 - - 77.7
21
Predicted
261
3D
6ckxD01 - 73.0
22
239 - - 84.1
23
235
3D
1d3uB02 - 95.4
24
229
3D
5l2wB01 - 91.8
25
227
3D
3o0gE00 - 69.0
27
212
3D
6gu4B01 - 86.5
26
209 - - 83.3
28
201 - - 78.5
29
195
3D
1kxuA02 - 96.6
30
182 - - 84.3
33
168
3D
4ellB02 - 81.1
31
168 - - 91.7
32
159 - - 95.4
35
150
3D
4yozA01 - 85.8
34
149 - - 88.9
39
131
3D
4ellB01 - 73.1
36
128 - - 75.5
38
119 - - 95.6
40
116 - - 97.8
41
112 - - 63.7
44
112
3D
1kxuA01 - 56.5
42
111 - - 98.3
43
111 - - 85.3
46
110
3D
5n9gF01 - 96.6
45
108 - - 87.8
47
104 - - 84.5
48
102 - - 70.9
49
100 - - 76.5
50
97 - - 44.6
51
97 - - 70.1
52
94 - - 78.1
53
92 - - 85.0
54
91
3D
3m03C00 - 98.0
55
83 - - 81.9
59
83
3D
4yozA02 - 73.6
57
81 - - 95.6
56
81 - - 72.5
60
80 - - 95.5
58
80 - - 75.7
62
79 - - 70.7
61
79 - - 64.0
63
73 - - 70.9
64
67 - - 91.1
65
65 - - 72.1
66
64 - - 79.6
68
62 - - 68.5
67
62 - - 80.2
69
60 - - 91.8
70
57 - - 94.4
71
55 - - 62.1
72
54 - - 80.4
74
53 - - 81.9
73
53 - - 73.8
75
51 - - 77.1
76
51
3D
1zp2A02 - 96.3
77
48 - - 75.2
78
47 - - 68.2
79
46 - - 74.8
80
46 - - 87.4
81
45 - - 84.3
82
43 - - 76.7
85
40
3D
2pmiD00 - 68.6
83
38 - - 76.8
84
37 - - 78.6
86
36 - - 70.0
87
35 - - 25.5
88
34 - - 74.2
89
33 - - 96.1
91
31 - - 75.7
90
31 - - 23.2
94
30 - - 44.5
93
30 - - 97.4
92
30 - - 45.3
95
AFU_orthologue AFUA_5G07030
29 - - 93.3
96
29 - - 84.0
97
28 - - 61.9
99
27 - - 13.3
98
27 - - 48.1
100
26 - - 76.5
101
25 - - 86.2
102
24 - - 10.6
103
24 - - 91.1
120
23
3D
3g33D02 - 73.9
104
23 - - 77.1
105
22 - - 57.3
110
21 - - 75.8
107
21 - - 63.9
106
21 - - 69.2
108
21 - - 89.5
109
21 - - 74.0
111
20 - - 84.7
112
19 - - 49.8
113
19 - - 0.0
198
19
3D
6gu4B02 - 54.9
114
19 - - 71.7
116
18 - - 5.2
115
18 - - 72.5
121
17 - - 90.9
117
17 - - 66.8
118
17 - - 42.1
119
17 - - 5.4
122
16 - - 92.2
127
16 - - 37.2
123
16 - - 76.8
125
16 - - 13.0
126
16 - - 72.5
124
16 - - 10.5
140
16
3D
5l2wB02 - 39.1
131
15 - - 38.2
129
15 - - 25.8
130
15 - - 16.6
132
15 - - 24.9
128
15 - - 65.4
138
14 - - 14.0
134
14 - - 79.8
139
14 - - 17.9
136
14 - - 7.6
135
14 - - 18.1
133
14 - - 30.8
137
14 - - 15.2
141
14 - - 94.3
142
14 - - 96.1
148
13 - - 8.2
149
13 - - 13.4
144
13 - - 11.1
146
13 - - 39.8
145
13 - - 46.1
143
Yin
13 - - 13.0
150
13 - - 68.5
147
13 - - 16.2
154
12 - - 76.0
152
12 - - 26.0
153
12 - - 91.7
151
12 - - 16.6
156
11 - - 34.6
162
11 - - 7.3
155
11 - - 32.8
160
11 - - 30.1
158
11 - - 34.7
163
11 - - 10.7
159
11 - - 86.4
161
11 - - 39.0
167
11 - - 73.8
166
11 - - 8.7
177
11
3D
4krdB00 - 1.9
165
11 - - 74.3
168
11 - - 16.5
157
11 - - 70.1
164
11 - - 45.5
179
10 - - 64.4
174
10 - - 11.6
178
10 - - 7.7
180
10 - - 94.5
175
10 - - 3.5
176
10 - - 79.6
181
10 - - 90.0
171
10 - - 24.1
173
10 - - 11.4
172
10 - - 25.8
170
10 - - 55.1
169
10 - - 38.9
182
9 - - 47.5
183
9 - - 84.0
187
9 - - 11.4
186
9 - - 6.8
185
9 - - 28.4
188
9 - - 0.0
189
9 - - 9.4
184
9 - - 51.7
193
8 - - 1.3
197
8 - - 6.6
191
8 - - 37.2
192
8 - - 84.3
190
8 - - 34.6
199
8 - - 77.9
194
8 - - 12.5
196
8 - - 1.3
195
8 - - 9.2
203
7 - - 18.6
221
7 - - 91.8
213
7 - - 1.9
207
7 - - 2.8
201
7 - - 81.5
223
7 - - 80.4
217
7 - - 7.3
211
7 - - 7.5
220
7 - - 79.0
222
7 - - 85.3
212
7 - - 44.2
202
7 - - 18.9
210
7 - - 1.8
200
7 - - 68.9
218
7 - - 42.8
208
7 - - 11.5
219
7 - - 58.4
209
7 - - 2.4
214
7 - - 4.7
204
7 - - 2.3
216
7 - - 9.6
206
7 - - 6.8
205
7 - - 14.0
215
7 - - 0.0
227
6 - - 85.4
236
6 - - 5.3
246
6 - - 83.1
245
6 - - 41.9
235
6 - - 12.9
248
6 - - 63.5
238
6 - - 12.6
244
6 - - 54.5
239
6 - - 3.8
249
6 - - 75.8
234
6 - - 8.5
224
6 - - 32.6
229
6 - - 76.6
240
6 - - 4.5
228
6 - - 80.2
232
6 - - 5.9
242
6 - - 15.2
230
6 - - 70.1
225
6 - - 75.5
233
6 - - 10.9
243
6 - - 4.6
247
6 - - 72.0
241
6 - - 3.5
237
6 - - 12.9
250
6 - - 76.5
231
6 - - 96.6
226
6 - - 42.7
275
5 - - 0.0
258
5 - - 32.0
263
5 - - 10.6
259
5 - - 30.5
267
5 - - 5.2
261
5 - - 0.0
254
5 - - 55.4
276
5 - - 0.0
256
5 - - 80.5
274
5 - - 3.9
279
5 - - 95.5
260
5 - - 1.1
278
5 - - 45.3
262
5 - - 2.4
255
5 - - 78.7
268
5 - - 2.1
270
5 - - 4.8
253
5 - - 63.8
272
5 - - 5.0
264
5 - - 3.4
269
5 - - 77.5
257
5 - - 38.4
251
5 - - 30.5
271
5 - - 0.0
277
5 - - 25.9
266
5 - - 9.7
252
5 - - 43.6
265
5 - - 0.0
273
5 - - 14.5
283
4 - - 81.9
320
4 - - 84.7
290
4 - - 37.9
310
4 - - 5.1
281
4 - - 42.1
287
4 - - 28.6
300
4 - - 87.2
312
4 - - 1.3
292
4 - - 8.0
302
4 - - 69.4
303
4 - - 6.4
293
4 - - 3.4
313
4 - - 4.4
301
4 - - 34.6
280
4 - - 34.1
307
4 - - 9.3
311
4 - - 23.2
291
4 - - 6.8
317
4 - - 51.4
297
4 - - 74.3
282
4 - - 42.3
288
4 - - 21.9
316
4 - - 43.6
296
4 - - 35.1
306
4 - - 0.0
305
4 - - 11.0
284
4 - - 65.9
315
4 - - 69.1
295
4 - - 7.7
289
4 - - 33.3
318
4 - - 82.8
298
4 - - 29.7
308
4 - - 0.0
286
4 - - 22.1
314
4 - - 12.3
294
4 - - 4.0
285
4 - - 13.0
304
4 - - 2.7
299
4 - - 92.0
319
4 - - 82.1
309
4 - - 7.6
322
3 - - 46.8
338
3 - - 2.6
356
3 - - 43.5
374
3 - - 76.4
348
CAK
3 - - 2.0
362
3 - - 6.9
349
3 - - 8.0
355
3 - - 49.4
334
3 - - 2.4
344
3 - - 0.0
360
3 - - 47.8
339
3 - - 0.0
346
3 - - 2.0
358
3 - - 3.1
363
3 - - 0.0
321
3 - - 29.5
327
3 - - 25.4
336
3 - - 0.0
335
3 - - 0.0
323
3 - - 19.4
354
3 - - 11.2
359
3 - - 7.9
361
3 - - 4.7
345
3 - - 9.2
367
3 - - 6.2
366
3 - - 0.0
343
3 - - 2.4
325
3 - - 34.5
333
3 - - 6.8
371
3 - - 63.8
331
3 - - 0.0
350
3 - - 7.9
337
3 - - 10.0
326
3 - - 27.8
373
3 - - 78.2
352
3 - - 0.0
341
3 - - 2.7
365
3 - - 0.0
347
3 - - 0.0
372
3 - - 47.6
329
3 - - 0.0
370
3 - - 37.6
368
3 - - 55.9
353
3 - - 0.0
324
3 - - 65.0
342
3 - - 6.8
369
3 - - 33.0
351
3 - - 0.0
330
3 - - 0.0
357
3 - - 14.7
364
3 - - 1.1
340
3 - - 5.6
332
3 - - 0.0
328
CAK
3 - - 1.9
379
2 - - 40.4
408
2 - - 5.5
429
2 - - 0.0
393
2 - - 16.7
472
2 - - 0.0
418
2 - - 0.0
453
2 - - 40.9
424
2 - - 0.0
470
2 - - 0.0
468
2 - - 2.0
451
2 - - 0.0
404
2 - - 0.0
457
2 - - 42.1
382
2 - - 37.1
430
2 - - 5.2
442
2 - - 0.8
469
2 - - 0.0
414
2 - - 2.3
432
2 - - 0.9
380
2 - - 31.0
378
2 - - 33.1
409
2 - - 0.0
428
2 - - 0.0
484
2 - - 44.2
397
2 - - 0.0
440
2 - - 0.0
419
2 - - 10.9
391
2 - - 50.9
464
2 - - 0.0
443
2 - - 2.8
466
AFU_orthologue AFUA_2G07660
2 - - 1.1
486
2 - - 15.3
383
2 - - 42.7
406
2 - - 0.0
477
2 - - 0.0
471
2 - - 0.0
433
2 - - 0.0
416
2 - - 0.0
425
2 - - 0.0
375
2 - - 33.8
415
2 - - 0.0
426
2 - - 12.0
392
2 - - 43.8
473
2 - - 3.6
376
2 - - 11.6
405
2 - - 0.0
431
2 - - 0.0
437
2 - - 0.9
450
2 - - 0.0
390
2 - - 63.4
465
2 - - 0.4
441
2 - - 0.0
447
2 - - 0.8
485
2 - - 47.0
452
2 - - 0.0
387
2 - - 39.4
381
2 - - 40.1
463
2 - - 1.3
386
2 - - 41.3
483
2 - - 38.8
446
2 - - 4.7
458
2 - - 13.2
413
2 - - 0.0
436
2 - - 0.0
398
2 - - 0.0
475
2 - - 29.2
421
2 - - 0.0
377
2 - - 36.7
403
2 - - 0.0
427
2 - - 2.0
399
2 - - 0.0
411
2 - - 10.4
417
2 - - 2.9
423
2 - - 1.7
401
2 - - 0.0
435
2 - - 0.0
407
2 - - 0.0
476
2 - - 40.7
454
2 - - 42.3
445
2 - - 0.0
461
2 - - 0.0
394
2 - - 17.1
481
2 - - 38.5
467
2 - - 5.3
385
2 - - 44.2
459
2 - - 2.7
422
2 - - 1.7
396
2 - - 30.0
438
2 - - 0.0
479
2 - - 0.0
388
2 - - 53.4
420
2 - - 0.0
474
2 - - 10.7
456
2 - - 44.1
448
2 - - 0.0
455
2 - - 40.6
389
2 - - 39.4
400
2 - - 1.1
434
2 - - 0.0
462
2 - - 0.0
410
2 - - 0.0
449
2 - - 6.9
482
2 - - 41.3
384
2 - - 40.8
402
2 - - 9.0
439
2 - - 0.0
478
2 - - 0.0
480
2 - - 33.6
412
2 - - 3.0
460
2 - - 0.0
444
2 - - 6.3
395
2 - - 16.8
563
1 - - 0.0
694
1 - - 0.0
652
1 - - 0.0
583
1 - - 0.0
641
1 - - 0.0
546
1 - - 0.0
665
1 - - 0.0
558
1 - - 0.0
496
1 - - 0.0
685
1 - - 0.0
647
1 - - 0.0
513
1 - - 0.0
605
1 - - 0.0
536
1 - - 0.0
699
1 - - 0.0
631
1 - - 0.0
721
1 - - 0.0
703
1 - - 0.0
575
1 - - 0.0
650
p107
1 - - 0.0
637
1 - - 0.0
626
1 - - 0.0
503
1 - - 0.0
521
1 - - 0.0
615
1 - - 0.0
488
1 - - 0.0
527
1 - - 0.0
673
1 - - 0.0
713
1 - - 0.0
633
1 - - 0.0
698
1 - - 0.0
625
1 - - 0.0
707
1 - - 0.0
511
1 - - 0.0
616
1 - - 0.0
723
1 - - 0.0
701
1 - - 0.0
517
1 - - 0.0
717
1 - - 0.0
501
1 - - 0.0
489
1 - - 0.0
677
1 - - 0.0
523
1 - - 0.0
606
1 - - 0.0
535
1 - - 0.0
554
1 - - 0.0
671
p130
1 - - 0.0
592
1 - - 0.0
711
1 - - 0.0
507
1 - - 0.0
576
1 - - 0.0
561
1 - - 0.0
587
1 - - 0.0
666
1 - - 0.0
545
1 - - 0.0
495
1 - - 0.0
686
1 - - 0.0
567
1 - - 0.0
581
1 - - 0.0
643
1 - - 0.0
590
1 - - 0.0
559
1 - - 0.0
684
1 - - 0.0
522
1 - - 0.0
640
1 - - 0.0
619
1 - - 0.0
593
1 - - 0.0
538
1 - - 0.0
664
1 - - 0.0
579
1 - - 0.0
632
1 - - 0.0
722
1 - - 0.0
695
1 - - 0.0
628
1 - - 0.0
609
1 - - 0.0
689
TFIIB
1 - - 0.0
642
1 - - 0.0
520
1 - - 0.0
669
1 - - 0.0
614
1 - - 0.0
556
1 - - 0.0
498
1 - - 0.0
651
1 - - 0.0
574
1 - - 0.0
720
1 - - 0.0
630
1 - - 0.0
657
1 - - 0.0
604
1 - - 0.0
548
1 - - 0.0
555
1 - - 0.0
710
1 - - 0.0
688
1 - - 0.0
670
1 - - 0.0
534
1 - - 0.0
668
1 - - 0.0
500
1 - - 0.0
700
1 - - 0.0
499
1 - - 0.0
562
1 - - 0.0
653
1 - - 0.0
510
1 - - 0.0
549
1 - - 0.0
624
1 - - 0.0
582
1 - - 0.0
502
1 - - 0.0
597
1 - - 0.0
591
1 - - 0.0
672
1 - - 0.0
539
1 - - 0.0
696
1 - - 0.0
712
1 - - 0.0
618
1 - - 0.0
580
1 - - 0.0
494
1 - - 0.0
578
1 - - 0.0
512
1 - - 0.0
629
1 - - 0.0
608
1 - - 0.0
560
1 - - 0.0
702
1 - - 0.0
544
1 - - 0.0
718
1 - - 0.0
680
1 - - 0.0
678
1 - - 0.0
612
1 - - 0.0
529
1 - - 0.0
660
1 - - 0.0
508
1 - - 0.0
644
1 - - 0.0
602
1 - - 0.0
697
1 - - 0.0
708
1 - - 0.0
572
1 - - 0.0
639
1 - - 0.0
691
1 - - 0.0
596
1 - - 0.0
518
1 - - 0.0
662
1 - - 0.0
553
1 - - 0.0
610
1 - - 0.0
649
1 - - 0.0
524
1 - - 0.0
682
1 - - 0.0
655
1 - - 0.0
588
1 - - 0.0
570
1 - - 0.0
634
1 - - 0.0
600
1 - - 0.0
568
1 - - 0.0
656
1 - - 0.0
714
1 - - 0.0
674
1 - - 0.0
551
1 - - 0.0
557
1 - - 0.0
530
1 - - 0.0
504
1 - - 0.0
648
1 - - 0.0
589
1 - - 0.0
704
1 - - 0.0
542
1 - - 0.0
620
1 - - 0.0
492
1 - - 0.0
569
1 - - 0.0
514
1 - - 0.0
719
1 - - 0.0
487
1 - - 0.0
679
1 - - 0.0
532
1 - - 0.0
595
1 - - 0.0
528
1 - - 0.0
509
1 - - 0.0
709
1 - - 0.0
490
1 - - 0.0
584
1 - - 0.0
622
1 - - 0.0
540
1 - - 0.0
519
1 - - 0.0
638
1 - - 0.0
693
1 - - 0.0
564
1 - - 0.0
543
1 - - 0.0
690
1 - - 0.0
659
1 - - 0.0
493
1 - - 0.0
687
1 - - 0.0
661
1 - - 0.0
645
1 - - 0.0
566
1 - - 0.0
586
1 - - 0.0
681
1 - - 0.0
667
1 - - 0.0
601
1 - - 0.0
506
1 - - 0.0
577
1 - - 0.0
623
1 - - 0.0
635
1 - - 0.0
692
1 - - 0.0
571
1 - - 0.0
716
1 - - 0.0
654
1 - - 0.0
676
1 - - 0.0
607
1 - - 0.0
598
1 - - 0.0
533
1 - - 0.0
525
1 - - 0.0
611
1 - - 0.0
516
1 - - 0.0
706
1 - - 0.0
617
1 - - 0.0
603
1 - - 0.0
526
1 - - 0.0
621
1 - - 0.0
515
1 - - 0.0
705
1 - - 0.0
573
1 - - 0.0
627
1 - - 0.0
613
1 - - 0.0
505
1 - - 0.0
636
1 - - 0.0
531
1 - - 0.0
599
1 - - 0.0
715
1 - - 0.0
675
1 - - 0.0
537
1 - - 0.0
550
1 - - 0.0
497
1 - - 0.0
541
1 - - 0.0
565
1 - - 0.0
646
1 - - 0.0
658
1 - - 0.0
491
1 - - 0.0
585
1 - - 0.0
547
1 - - 0.0
663
1 - - 0.0
552
1 - - 0.0
594
1 - - 0.0
683
1 - - 0.0
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