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CATH Superfamily 1.10.1670.10

Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Endonuclease III
789
3D
 2abkA02 - 83.9
2
Adenine DNA glycosylase
391
3D
 1weiA01 - 93.0
5
N-glycosylase/DNA lyase OGG1
245
3D
 6g40C02 - 98.0
3
Endonuclease III homolog
229 - - 89.6
4
DNA glycosylase/AP lyase ROS1
215 - - 57.4
7
DNA-3-methyladenine glycosylase 2
99
3D
 3oh9A03 - 28.2
6
A/G-specific adenine glycosylase
63 - - 39.3
8
Endonuclease III
46 - - 19.8
9
DNA-3-methyladenine glycosylase 2 family protein
37 - - 84.2
10
DNA-3-methyladenine glycosylase II
33 - - 26.4
11
N-glycosylase/DNA lyase, putative
18 - - 7.3
12
8-oxoguanine DNA glycosylase
18 - - 14.9
13
8-oxoguanine DNA glycosylase
18 - - 77.7
15
Endonuclease III homolog
17 - - 5.8
14
Adenine DNA glycosylase
17 - - 19.6
16
Endonuclease III
16 - - 47.1
18
Endonuclease III
16 - - 54.3
17
Related to 8-oxoguanine DNA-glycosylase
16 - - 69.8
19
Endonuclease III
15 - - 80.6
20
Adenine DNA glycosylase
14 - - 16.9
21
Endonuclease III homolog
13 - - 38.9
24
Endonuclease III homolog
12 - - 21.0
23
Endonuclease III homolog
12 - - 61.6
22
Adenine DNA glycosylase
12 - - 13.9
25
Ogg1p
11 - - 73.3
26
Endonuclease III homolog
10 - - 36.6
27
Endonuclease III homolog
9 - - 63.3
29
Endonuclease III homolog
8 - - 38.3
28
A/G-specific adenine glycosylase
8 - - 0.0
30
A/G-specific adenine glycosylase, putative
7 - - 3.4
32
Endonuclease III, putative
6 - - 4.6
31
Endonuclease III, putative
6 - - 8.8
33
Endonuclease III homolog
6 - - 12.2
34
Adenine DNA glycosylase
6 - - 58.4
35
Endonuclease III homolog
5 - - 23.6
36
Endonuclease III homolog
5 - - 69.5
37
4 - - 14.9
39
Adenine DNA glycosylase
4 - - 0.0
41
4 - - 12.8
40
4 - - 3.8
38
4 - - 0.0
47
3 - - 31.2
43
3 - - 5.7
45
3 - - 0.0
42
3 - - 6.5
46
3 - - 3.4
44
3 - - 0.0
55
2 - - 12.0
57
2 - - 0.0
58
2 - - 0.0
49
2 - - 0.0
52
2 - - 0.0
51
2 - - 0.0
48
2 - - 0.0
50
2 - - 8.3
56
2 - - 0.0
54
2 - - 2.1
59
2 - - 44.7
53
2 - - 0.0
71
1 - - 0.0
73
1 - - 0.0
76
1 - - 0.0
62
1 - - 0.0
67
1 - - 0.0
74
1 - - 0.0
61
1 - - 0.0
77
1 - - 0.0
64
1 - - 0.0
68
1 - - 0.0
83
1 - - 0.0
78
1 - - 0.0
65
1 - - 0.0
81
1 - - 0.0
60
1 - - 0.0
82
1 - - 0.0
69
1 - - 0.0
79
1 - - 0.0
63
1 - - 0.0
80
1 - - 0.0
72
1 - - 0.0
66
1 - - 0.0
70
1 - - 0.0
75
1 - - 0.0