CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.80 | Alpha-Beta Horseshoe |
|
3.80.10 | Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) |
|
3.80.10.10 | Ribonuclease Inhibitor |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease Inhibitor |
| Functional Family | Toll-like receptor 7 |
Enzyme Information
UniProtKB Entries (1)
| Q9NR97 |
TLR8_HUMAN
Homo sapiens
Toll-like receptor 8
|
PDB Structure
| PDB | 5WYZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Small-molecule inhibition of TLR8 through stabilization of its resting state
Nat. Chem. Biol.
|