1 keywords

CATH Domain 5jzxD03

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.78 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1
Homologous Superfamily 3.90.78.10 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain

Domain Context

CATH Clusters

Superfamily UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Functional Family

Enzyme Information

1.3.1.98
UDP-N-acetylmuramate dehydrogenase.
based on mapping to UniProt P9WJL9
UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.
-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

UniProtKB Entries (1)

P9WJL9
MURB_MYCTU
Mycobacterium tuberculosis H37Rv
UDP-N-acetylenolpyruvoylglucosamine reductase

PDB Structure

PDB 5JZX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) from Mycobacterium tuberculosis
Eniyan, K., Dharavath, S., Vijayan, R., Bajpai, U., Gourinath, S.
Biochim. Biophys. Acta