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1 keywords

CATH Domain 4fgyA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Peroxisome proliferator-activated receptor gamma

Enzyme Information

UniProtKB Entries (1)

P37231
PPARG_HUMAN
Homo sapiens
Peroxisome proliferator-activated receptor gamma

PDB Structure

PDB 4FGY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor Gamma (PPAR-gamma) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes.
Zheng, W., Feng, X., Qiu, L., Pan, Z., Wang, R., Lin, S., Hou, D., Jin, L., Li, Y.
Diabetologia
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