CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1280.10
Functional Family

Enzyme Information

2.1.1.177
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase.
based on mapping to UniProt P0C1V0
S-adenosyl-L-methionine + pseudouridine(1915) in 23S rRNA = S-adenosyl-L- homocysteine + N(3)-methylpseudouridine(1915) in 23S rRNA.
-!- YbeA does not methylate uridine at position 1915.

UniProtKB Entries (1)

P0C1V0
RLMH_STAAU
Staphylococcus aureus
Ribosomal RNA large subunit methyltransferase H

PDB Structure

PDB 4FAK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Characterization of the Staphylococcus aureus rRNA Methyltransferase Encoded by orfX, the Gene Containing the Staphylococcal Chromosome Cassette mec (SCCmec) Insertion Site.
Boundy, S., Safo, M.K., Wang, L., Musayev, F.N., O'Farrell, H.C., Rife, J.P., Archer, G.L.
J.Biol.Chem.