CATH Classification

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Peroxisome proliferator-activated receptor gamma

Enzyme Information

UniProtKB Entries (1)

Q15788
NCOA1_HUMAN
Homo sapiens
Nuclear receptor coactivator 1

PDB Structure

PDB 3S9S
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARgamma partial agonist.
Sime, M., Allan, A.C., Chapman, P., Fieldhouse, C., Giblin, G.M., Healy, M.P., Lambert, M.H., Leesnitzer, L.M., Lewis, A., Merrihew, R.V., Rutter, R.A., Sasse, R., Shearer, B.G., Wilson, T.M., Xu, R.X., Virley, D.J.
Bioorg.Med.Chem.Lett.