CATH Domain 3ljtA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.390	Collagenase (Catalytic Domain)
	3.40.390.10	Collagenase (Catalytic Domain)

Domain Context

CATH Clusters

Superfamily	Collagenase (Catalytic Domain)
Functional Family	A disintegrin and metalloproteinase with thrombospondin motifs 1

Enzyme Information

3.4.24.-

Metalloendopeptidases.

based on mapping to UniProt Q9UNA0

UniProtKB Entries (1)

ATS5_HUMAN

Homo sapiens

A disintegrin and metalloproteinase with thrombospondin motifs 5

PDB Structure

PDB	3LJT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure analysis reveals the flexibility of the ADAMTS-5 active site. Shieh, H.S., Tomasselli, A.G., Mathis, K.J., Schnute, M.E., Woodard, S.S., Caspers, N., Williams, J.M., Kiefer, J.R., Munie, G., Wittwer, A., Malfait, A.M., Tortorella, M.D. Protein Sci.