CATH Domain 3ky9A03

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Vav guanine nucleotide exchange factor 2

Enzyme Information

UniProtKB Entries (1)

VAV_HUMAN

Homo sapiens

Proto-oncogene vav

PDB Structure

PDB	3KY9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1 Yu, B., Martins, I.R., Li, P., Amarasinghe, G.K., Umetani, J., Fernandez-Zapico, M.E., Billadeau, D.D., Machius, M., Tomchick, D.R., Rosen, M.K. Cell(Cambridge,Mass.)