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1 keywords

CATH Domain 3knxC01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.10 Thrombin, subunit H
Homologous Superfamily 2.40.10.120  

Domain Context

CATH Clusters

Superfamily 2.40.10.120
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q9ELS8
Q9ELS8_9HEPC
Hepatitis C virus subtype 1a
Genome polyprotein

PDB Structure

PDB 3KNX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 protease.
Venkatraman, S., Velazquez, F., Wu, W., Blackman, M., Chen, K.X., Bogen, S., Nair, L., Tong, X., Chase, R., Hart, A., Agrawal, S., Pichardo, J., Prongay, A., Cheng, K.C., Girijavallabhan, V., Piwinski, J., Shih, N.Y., Njoroge, F.G.
J.Med.Chem.
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