CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | Immunoglobulin kappa constant |
Enzyme Information
UniProtKB Entries (1)
| P00533 |
EGFR_HUMAN
Homo sapiens
Epidermal growth factor receptor
|
PDB Structure
| PDB | 3C09 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Mus |
| Primary Citation |
Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization.
Cancer Cell
|
