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CATH Classification

Domain Context

CATH Clusters

Superfamily DHBP synthase
Functional Family Threonylcarbamoyl-AMP synthase

Enzyme Information

2.7.7.87
L-threonylcarbamoyladenylate synthase.
based on mapping to UniProt Q970S6
L-threonine + ATP + HCO(3)(-) = L-threonylcarbamoyladenylate + diphosphate + H(2)O.
-!- The enzyme is involved in the synthesis of N(6)- threonylcarbamoyladenosine(37) in tRNAs with the anticodon NNU, i.e. tRNA(Ile), tRNA(Thr), tRNA(Asn), tRNA(Lys), tRNA(Ser) and tRNA(Arg).

UniProtKB Entries (1)

Q970S6
SUA5_SULTO
Sulfurisphaera tokodaii str. 7
Threonylcarbamoyl-AMP synthase

PDB Structure

PDB 3AJE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Sulfolobus tokodaii Sua5 complexed with L-threonine and AMPPNP
Kuratani, M., Kasai, T., Akasaka, R., Higashijima, K., Terada, T., Kigawa, T., Shinkai, A., Bessho, Y., Yokoyama, S.
Proteins
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