1 keywords

CATH Domain 2vr2A01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.140 Metal-dependent hydrolases

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family Dihydropyrimidinase like 2

Enzyme Information

3.5.2.2
Dihydropyrimidinase.
based on mapping to UniProt Q14117
5,6-dihydrouracil + H(2)O = 3-ureidopropanoate.
-!- Also acts on dihydrothymine and hydantoin.

UniProtKB Entries (1)

Q14117
DPYS_HUMAN
Homo sapiens
Dihydropyrimidinase

PDB Structure

PDB 2VR2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Crystal Structure of Human Dihydropyrimidinase
Welin, M., Karlberg, T., Andersson, J., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, I., Kallas, A., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Wikstrom, M., Nordlund, P.
To be Published