CATH Domain 2lozA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Tensin 1

Enzyme Information

3.1.3.-

Phosphoric monoester hydrolases.

based on mapping to UniProt Q63HR2

UniProtKB Entries (1)

RHG07_HUMAN

Homo sapiens

Rho GTPase-activating protein 7

PDB Structure

PDB	2LOZ
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode. Chen, L., Liu, C., Ko, F.C., Xu, N., Ng, I.O., Yam, J.W., Zhu, G. J.Biol.Chem.